As per a recent study by Dr. Kaitlin Wade from the University of Bristol. It has been discovered that a particular type of bacteria in the gut microbiome can increase the risk of bowel cancer by 2% to 15%. This bacteria is known as Bacteroidales in medical terms. And is the main trigger of Bowel Cancer.
The said study used a technique called Mendelian randomization. Through which it has been discovered that people who have bowel cancer carry large quantities of bacteroidales in their guts. This is in contrast to the people who do not have bowel cancer.
The community of microbes transpires naturally in the human body. It is referred to as microbiomes. As per recent research, microbiomes play a vital role in making the human body vulnerable to diseases. Gut bacteria are considered good for digestion, maintaining intestinal health and provides safety against infections. Studies show that gut bacteria remain unchanged throughout the lifetime of an individual except for any illness or changes in the diet affects it. However, the gut microbiome is different for different individuals depending upon their genes and environment.
Several experiments have been done on mice and humans as well. However, it is still uncertain what triggers bowel cancer. It is also not confirmed whether cancer causes increased quantities of gut bacteria or there are other factors involved as well. Researchers are yet to find out if changes in the gut microbiome can be the cause of bowel cancer or not. Moreover, some scientists also suggest that few microbiomes also cause other diseases like obesity and anxiety.
About 4000 people from different parts of Europe are part of the project to find any link between gut bacteria and bowel cancer. The study is trying to find out whether people who naturally have the variant are likely to form cancer cells in the bowel area or not. The direct link hasn’t been found yet because gut microbiomes develop at the start of early life, which means some people may carry the cancer gene from the start. Or certain changes in diets can trigger an increase in the formation of bacteroidales in the gut microbiome and increase the risk of bowel cancer.