Here comes interesting news for the people with allergies. Imagining how humanity has suffered from the consequences of all kinds of different allergic reactions is undefined. Recently, John Holloway, professor of Allergy and Respiratory Genetics within Medicine at the University of Southampton, introduces his discovery of the relationship between an individual’s season of birth and allergy risks, which could potentially provide a solution for chronic allergies.
According to his article, “Association of season of birth with DNA methylation and allergic disease” published by John Wiley and Sons, shows that birth season has triggered DNA methylation, a process of controlling and expressing our genes within our DNAs. His study had 367 subjects of 18-year-old from the Isle of Wight cohort. By monitoring and analyzing their blood samples they measured associations and relations among their DNA methylation, birth season and allergy. The risks of birth season on allergic results were able to be estimated because certain allergies have appeared to subjects who share same birth season and they lasted in their DNA for a long period of time since their birth. Especially, the subjects who were born in fall or winter were in higher exposure of Asthma and Mite Allergy (PIAMA) than those who were born in summer or spring. Moreover, this result was shown in the cohort of 8-years-old but not in that of newborn. His article suggests that our birth month determines the types of our allergy and demonstrates that DNA methylation takes place after birth. Unfortunately, he concluded that it is just a hypothesis due to some unmodified causes, specific seasonal variations and their effects. Then, he added that further study is needed to pinpoint those causes.
On the condition that his hypothesis continues and identifies the causes, the article will be a delighted news for those people suffering from chronic allergy. Let’s believe that his discovery was the first step to the next level of gene manipulation to cure and prevent allergy disease in the coming future.